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Search for "LecA inhibition" in Full Text gives 1 result(s) in Beilstein Journal of Organic Chemistry.

Efficient synthesis of phenylene-ethynylene rods and their use as rigid spacers in divalent inhibitors

  • Francesca Pertici,
  • Norbert Varga,
  • Arnoud van Duijn,
  • Matias Rey-Carrizo,
  • Anna Bernardi and
  • Roland J. Pieters

Beilstein J. Org. Chem. 2013, 9, 215–222, doi:10.3762/bjoc.9.25

Graphical Abstract
  • phenylene units. Preliminary applications of these rods in divalent systems are shown. Inhibition studies with Pseudomonas Aeruginosa lectin LecA showed that the rigid spacer proved greatly beneficial for the inhibitory potency. Keywords: multivalent carbohydrates; LecA inhibition; phenylene ethynylene
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Published 31 Jan 2013
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